Diet high in a certain fat may help weight loss
Scientists say that , after a diet rich in a particular type of fat can increase metabolism and help people lose weight. This is according to a study published in The Journal of Lipid Research.
Researchers from Texas Tech University say their findings could lead to the development of supplements and a diet that could accelerate metabolism and reduce muscle fatigue.
The researchers say that the skeletal muscles of obese people containing a particular enzyme called SCD1 , which is capable of breaking down saturated fats.
SCD1 works by converting saturated monounsaturated fat , which is easier to metabolize .
Normally, the liver produces this enzyme depends on the fat content of the food consumed , researchers say , and adipose tissue fatty acids always produces the enzyme as a means to regulate .A big man with a tape measure around her waistThe researchers found that an enzyme present in skeletal muscle of obese , SCD1 , increases metabolism and energy in a study in mice and could lead to human dietary supplements.
However , the researchers say that the enzyme also occurs in which highly trained or obese skeletal muscle.
To determine the exact mechanisms of SCD1 , decided to genetically engineer mice so that your muscles are continuously produced the enzyme.SCD1 increased metabolism and energy
The researchers then compared the skeletal genetically modified mice with wild mouse muscle.
Genetically modified mice showed high levels of polyunsaturated fatty acids , compared to wild-type mice , particularly linoleic acid that can enter the body through diet. This meant that the modified mice consumed more food.
However, the study showed that the modified mice weighed less and increased exercise capacity compared to wild-type mice .
Ched Paton , assistant professor of nutritional biochemistry in the Department of Nutrition, Hospitality and Trade at Texas Tech University , explains:
"We found in genetically modified animals were hypermetabolic rates. They increased their energy consumption , and experience increased exercise capacity . "
"For example, the wheels of the year , normal mice fatigue after 7-10 minutes. These genetically modified animals would not fatigue for about 70 minutes. Then they ran a little longer . "
Enzyme causes "decoupling" of the DNA of muscle
Therefore, the researchers wanted to delve into what happened in skeletal muscle.
They found that SCD1 increased with increased consumption of food produced more linoleic acid in muscle tissue .
The acid then triggers the DNA of the muscle cell , which in turn stimulate the cells to create more mitochondria , and " light " a protein which induces the cell to burn the excess energy of the food, as additional heat . The researchers call this "decoupling" .Potential new food supplements
Professor Paton said their findings could lead to the human food supplementation to achieve the same result:
" You can not change the human genome, but it gives us an idea of whether you can activate the same part of the human DNA in the skeletal muscles burn excess energy as heat instead of storing . "He adds:
" It may be an additional people might have to turn on the metabolic unit cells , burn calories and increase mitochondria ."
Researchers from Texas Tech University say their findings could lead to the development of supplements and a diet that could accelerate metabolism and reduce muscle fatigue.
The researchers say that the skeletal muscles of obese people containing a particular enzyme called SCD1 , which is capable of breaking down saturated fats.
SCD1 works by converting saturated monounsaturated fat , which is easier to metabolize .
Normally, the liver produces this enzyme depends on the fat content of the food consumed , researchers say , and adipose tissue fatty acids always produces the enzyme as a means to regulate .A big man with a tape measure around her waistThe researchers found that an enzyme present in skeletal muscle of obese , SCD1 , increases metabolism and energy in a study in mice and could lead to human dietary supplements.
However , the researchers say that the enzyme also occurs in which highly trained or obese skeletal muscle.
To determine the exact mechanisms of SCD1 , decided to genetically engineer mice so that your muscles are continuously produced the enzyme.SCD1 increased metabolism and energy
The researchers then compared the skeletal genetically modified mice with wild mouse muscle.
Genetically modified mice showed high levels of polyunsaturated fatty acids , compared to wild-type mice , particularly linoleic acid that can enter the body through diet. This meant that the modified mice consumed more food.
However, the study showed that the modified mice weighed less and increased exercise capacity compared to wild-type mice .
Ched Paton , assistant professor of nutritional biochemistry in the Department of Nutrition, Hospitality and Trade at Texas Tech University , explains:
"We found in genetically modified animals were hypermetabolic rates. They increased their energy consumption , and experience increased exercise capacity . "
"For example, the wheels of the year , normal mice fatigue after 7-10 minutes. These genetically modified animals would not fatigue for about 70 minutes. Then they ran a little longer . "
Enzyme causes "decoupling" of the DNA of muscle
Therefore, the researchers wanted to delve into what happened in skeletal muscle.
They found that SCD1 increased with increased consumption of food produced more linoleic acid in muscle tissue .
The acid then triggers the DNA of the muscle cell , which in turn stimulate the cells to create more mitochondria , and " light " a protein which induces the cell to burn the excess energy of the food, as additional heat . The researchers call this "decoupling" .Potential new food supplements
Professor Paton said their findings could lead to the human food supplementation to achieve the same result:
" You can not change the human genome, but it gives us an idea of whether you can activate the same part of the human DNA in the skeletal muscles burn excess energy as heat instead of storing . "He adds:
" It may be an additional people might have to turn on the metabolic unit cells , burn calories and increase mitochondria ."
